eCOA/ePRO Benchmarking & Market Dynamics (6th Ed.)

Report Overview

Although clinical outcomes assessments (COAs) and patient reported outcomes (PROs) were originally collected and reviewed on paper, their electronic successors (eCOA/ePRO) have eclipsed paper as the preferred data collection method. eCOA/ePRO systems can offer an easier user experience, better response rates, higher quality data, and faster trials. However, eCOA/ePRO providers must always be on the lookout for new trends and needs in the market such as the need for improved integration with other technologies, increasing use of patient-owned devices, and incorporating Artificial Intelligence capabilities into eCOA/ePRO systems.

ISR has refreshed our eCOA/ePRO Benchmarking and Market Dynamics report with two main goals in mind:

1. Help pharma sponsor organizations and CROs make more informed eCOA/ePRO selection decisions –

This report contains a wealth of information on the provider selection process, including the criteria that are most important in choosing an eCOA/ePRO provider and the functions and factors that influence outsourcing decisions. Sponsor organizations and CROs can learn how individual providers perform along key attributes such as Ease of use for patients, Real-time data access, Flexibility for mid-study design changes, and more.

2. Help eCOA/ePRO providers optimize operational and marketing strategies –

This research measures key aspects of brand strength of 21 eCOA/ePRO solutions on the market and offers a pulse on trends such as desired improvements to eCOA/ePRO systems and a breakdown of the expected sources of reported outcomes. Also new in this version, respondents rated their overall satisfaction with recently used eCOA/ePRO providers and described why they assigned that satisfaction rating. eCOA/ePRO providers can use these insights to understand more about their strengths and weaknesses and focus on the capabilities that matter most.

We surveyed 130 experienced eCOA/ePRO outsourcers and collected their insights on 370 recent encounters with service providers. Respondents evaluate recently used eCOA/ePRO providers on their performance across 22 key attributes.

• Data collection in Q3, 2025
• 25-minute web-based quantitative survey
• 130 respondents from North America, Europe, Asia-Pacific, and Latin America
• 370 service encounters captured

What you will learn:

Pharmaceutical, Biopharma, or Biotech Sponsor Organizations and CROs:

• Understand how eCOA/ePRO providers are performing along a variety of attributes and consider which providers might be a good fit for your studies
• Learn how others in the outsourcing community are evaluating and maintaining relationships with their favorite providers
• See how recent users rated their overall satisfaction with eCOA/ePRO solutions and read verbatim responses on why they assigned that satisfaction rating

eCOA/ePRO Service Providers:

• Utilize the experience of recent customers to benchmark eCOA/ePRO provider performance across 22 attributes to gauge the performance of your company against users’ expectations
• Understand how your brand is perceived in the marketplace, including leadership perceptions and respondent awareness and familiarity with your offering
• Understand how sponsors and CROs choose eCOA/ePRO providers including selection attributes, use of preferred providers, contracting preferences, etc.
• Discover outsourcers’ perspectives on recent trends in the market including the use of AI, sources and collection methods for clinical outcomes assessments, direct data capture from sensors/wearables, and more

Major Sections:

• eCOA/ePRO Service Provider Selection Process
• eCOA/ePRO Trends
• eCOA/ePRO Service Provider Perceptions
• eCOA/ePRO Service Provider Performance
• Company Service Quality Profiles
• Appendix
• Service Provider Drill-downs
• Demographics

Performance Attributes:

• Ability for patients to choose data input method (e.g., app, web, etc.)
• Ability to support a variety of devices, including smartphones and BYOD
• Availability of validated questionnaire instruments / access to COA library
• Configurability for different study types
• Continuous data monitoring for patient safety
• Country-level support (including translations)
• Data security / patient privacy
• Ease of use for patients
• Ease of use for sites
• Ease of use for sponsors/CROs
• Expertise in COA selection and validation
• Flexibility for mid-study design changes
• Integration with eConsent, EDC, IRT, and other data systems
• Integration with sensors & wearable devices
• Post-study data delivery
• Process for dealing with data discrepancies / query resolution
• Project manager quality
• Real-time data access
• Reporting / data visualization capabilities
• Solutions to ensure good patient compliance with making diary entries
• Start-up timelines, platform build speed
• Technical support / training for sites

Included Providers:

• Castor ePRO
• Clario eCOA
• ClinCapture Captivate eCOA/ePRO
• Clinical ink eCOA
• Crucial Data Solutions TrialKit eCOA/ePRO
• Curebase ePRO
• Ennov ePRO
• ICON Digital Platform eCOA
• IQVIA eCOA
• Medable eCOA+
• Medidata eCOA
• Medpace TrialPACE eCOA/ePRO
• Medrio eCOA/ePRO
• Merative Zelta eCOA
• OpenClinica Participate ePRO
• Signant Health SmartSignals eCOA
• Suvoda eCOA
• uMotif eCOA/ePRO
• Veeva eCOA
• Viedoc eCOA/ePRO
• YPrime eCOA

Companies listed in bold print have been reviewed by 10 or more respondents. These providers have detailed company service quality profiles and are included in an in-depth performance analysis.